Can I Combine Daxxify with Other Treatments for Better Results?

Daxxify combination treatments at Columbine Aesthetics — experience peptide-powered wrinkle reduction and radiant skin by calling (720) 504-4407 today to schedule your consultation

Summary Highlights:

Daxxify pairs beautifully with fillers, peels, and microneedling for a holistic anti-aging approach.
Peptide Exchange Technology™ delivers smoother, longer-lasting wrinkle reduction.
Safe and expertly administered by a licensed Nurse Practitioner.
Customized treatment plans ensure natural, balanced, and lasting results.

When it comes to wrinkle reduction, Daxxify® has completely redefined what’s possible in aesthetic medicine. At Columbine Aesthetics, we often get asked whether Daxxify can be combined with other treatments for enhanced, longer-lasting results—and the answer is absolutely yes. As a nurse practitioner-owned aesthetic practice, we specialize in creating safe, customized combination treatments that rejuvenate your skin from multiple angles. Daxxify’s peptide-powered formula not only relaxes dynamic wrinkles but also complements other therapies that restore volume, improve texture, and boost collagen.

Why Is Daxxify the Perfect Foundation for Combination Treatments?

Unlike traditional neurotoxins such as Botox®, Dysport®, or Xeomin®, Daxxify uses Peptide Exchange Technology™—a proprietary stabilizing system that relies on clean, peptide-based ingredients rather than human or animal proteins. This innovation allows Daxxify to last up to six to nine months, making it ideal for patients who want sustained results and fewer maintenance visits. Because it provides a smooth, refreshed base, Daxxify becomes an excellent starting point for enhancing other treatments. Its long duration means you can schedule complementary procedures strategically, targeting multiple layers of aging—from muscle relaxation to skin renewal.

What Treatments Pair Best with Daxxify for Enhanced Anti-Aging?

At Columbine Aesthetics, we believe in designing holistic, synergistic treatment plans that reflect each client’s goals and lifestyle. Depending on your unique skin needs, we may recommend pairing Daxxify with the following:

Dermal Fillers: Combine Daxxify with fillers from the RHA® Collection or Radiesse® to restore volume, smooth deeper lines, and achieve balanced facial harmony. While Daxxify relaxes expression lines, fillers contour and rejuvenate.
Microneedling with AnteAGE® Growth Factors: Stimulate collagen and elastin production while Daxxify smooths dynamic wrinkles. Together, they firm, tighten, and revitalize the skin’s texture from within.
VI Peel® or PCA SKIN® Peels: Exfoliate dull, damaged skin while Daxxify addresses muscle-related wrinkles. This pairing creates a brighter, even-toned complexion that enhances the injectable’s effects.
Hyperdilute Radiesse®: A perfect match for Daxxify, this collagen-stimulating treatment firms crepey or lax skin, improving elasticity while maintaining natural movement.

Each of these pairings amplifies your results without compromising comfort or recovery time.

Is It Safe to Combine Daxxify with Other Procedures?

Safety is always our highest priority at Columbine Aesthetics. All combination plans are customized and performed by a licensed Nurse Practitioner with advanced training in facial anatomy and medical aesthetics. Because Daxxify injectable treatment is an FDA-approved neurotoxin formulated with a clean, peptide-based stabilizer, it works harmoniously with other medical-grade treatments. Most combinations can be performed during the same appointment or spaced strategically for optimal results, depending on your treatment goals. Typical post-treatment effects—such as mild redness or swelling—are temporary and subside quickly. We’ll guide you through every step to ensure your experience is comfortable, safe, and rewarding.

How Can I Personalize My Combination Treatment Plan?

Your Daxxify journey begins with a comprehensive consultation at Columbine Aesthetics. We evaluate your skin condition, muscle movement, and facial balance before recommending a customized plan. For example, if your main concern is forehead lines and loss of elasticity, we may pair Daxxify with Hyperdilute Radiesse® for a lifting effect. If uneven tone or dullness is your priority, we may suggest VI Peel® or PCA Skin® treatments to brighten your complexion. This individualized approach ensures that every Daxxify combination supports your long-term skin health and aesthetic goals.

What Results Can I Expect When Combining Treatments?

When you combine Daxxify with complementary treatments, the results are multidimensional—smoother skin, improved texture, and a more youthful glow. Thanks to Daxxify’s Peptide Technology, this advanced injectable not only lasts longer than traditional neurotoxins but also enhances how your skin responds to rejuvenating treatments. The peptide-powered formulation helps support smoother integration and longer-lasting balance between procedures, giving your complexion a naturally refreshed appearance over time.
At Columbine Aesthetics, many of our clients notice:

Softer expression lines and smoother forehead creases
Brighter, more even skin tone and texture
Increased collagen and elasticity
A refreshed, natural appearance that lasts

With ongoing maintenance and a medical-grade skincare routine, your rejuvenated look can stay consistent for months.

Choose Columbine Aesthetics for Daxxify Combination Treatments

At Columbine Aesthetics, we blend science, artistry, and clinical expertise to help you look and feel your best. Every treatment—whether it’s Daxxify alone or a full rejuvenation plan—is performed with precision and care. Our goal is not to change how you look but to enhance your natural features for confident, graceful aging. If you’re ready to experience the synergy of peptide-powered wrinkle reduction and collagen renewal, Daxxify combination treatments at Columbine Aesthetics are the perfect solution. Call (720) 504-4407 today to schedule your consultation or book online through our website and start your journey toward radiant, age-defying skin.

FAQs About Daxxify Injections

Common Questions About Botox Injections

What are Daxxify injections and how do they work?

Daxxify injections are an advanced FDA-approved neurotoxin treatment used to smooth moderate to severe frown lines (glabellar lines). Unlike traditional wrinkle relaxers like Botox or Dysport, Daxxify utilizes Peptide Exchange Technology to enhance the botulinum toxin’s binding to nerve receptors, thereby reducing muscle movement that causes wrinkles. This unique formulation allows for longer-lasting results, often extending up to 6 months or more.

How is Daxxify different from Botox, Dysport, or Xeomin?

While Daxxify, Botox, Dysport, and Xeomin are all botulinum toxin-based treatments, Daxxify is the first to use a proprietary stabilizing peptide instead of human or animal-based proteins. This innovation leads to longer-lasting wrinkle reduction, fewer treatments per year, and a cleaner formulation. Patients who want fewer visits and extended results often prefer Daxxify over Botox.

What areas can be treated with Daxxify?

Daxxify injections are currently FDA-approved for treating glabellar lines (frown lines between the eyebrows). Still, providers often use it off-label to treat other facial areas such as forehead lines, crow’s feet, and bunny lines. As with all aesthetic neurotoxins, treatment areas and dosage should be tailored by a skilled medical provider based on your goals and facial anatomy.

How long do the results from Daxxify injections last?

Clinical studies show that Daxxify results can last up to 6 months, with some patients seeing wrinkle reduction for even 9 months or longer. This duration is significantly longer than Botox, which typically lasts 3–4 months. The extended results mean fewer appointments and long-term wrinkle smoothing.

Is Daxxify safe?

Yes, Daxxify is FDA-approved and has undergone extensive clinical testing for safety and efficacy. Like all botulinum toxin treatments, minor side effects may include temporary redness, swelling, or tenderness at the injection site. It’s important to have Daxxify administered by a licensed medical professional to minimize risk and ensure optimal results.

Who is a good candidate for Daxxify injections?

Ideal candidates for Daxxify are adults who want to reduce facial wrinkles, especially between the brows, and are seeking longer-lasting alternatives to Botox. It’s also an excellent option for those new to anti-aging injections, as it offers a more extended treatment window with fewer touch-ups. Patients should be in good overall health and have realistic expectations.

How much do Daxxify injections cost?

At Columbine Aesthetics, Daxxify is priced at $11 per unit, with the total cost depending on the treatment area and units used. While Daxxify may have a slightly higher upfront price compared to other neurotoxins, its longer duration means fewer sessions over the course of a year, making it a valuable investment in youthful skin longevity.

What is the downtime or recovery like with Daxxify?

Daxxify is a minimally invasive treatment with virtually no downtime. Most clients return to normal activities immediately after their session. Some may experience mild bruising or swelling at the injection site, which typically resolves within a few hours to a day. For best results, avoid lying down or engaging in strenuous activity for approximately 4 hours after the injection.

Can Daxxify be combined with other cosmetic treatments?

Yes, Daxxify can safely be combined with other aesthetic services such as dermal fillers, microneedling, chemical peels, or medical-grade skincare to create a comprehensive anti-aging treatment plan. At Columbine Aesthetics, your treatment is customized to align with your goals, ensuring synergistic results and skin rejuvenation.

Why should I get Daxxify injections at Columbine Aesthetics?

At Columbine Aesthetics, your Daxxify treatment is performed by a licensed Nurse Practitioner with deep clinical knowledge of facial anatomy and injectables. We prioritize natural-looking results, safety, and personalized care. You’ll also benefit from expert guidance on how Daxxify fits into your broader anti-aging and skincare routine, all in a supportive, patient-first environment.

Why Trust Columbine Aesthetics

At Columbine Aesthetics, we believe your aesthetic journey should be as unique as you are. Led by Allison Page, NP-C, our highly skilled Nurse Practitioner with over 20 years of healthcare experience, we combine medical expertise with an artistic eye to deliver natural, beautiful results that enhance — not alter — your appearance.

We specialize in helping clients make informed, confident decisions about treatments such as Dysport® and Botox®. While both smooth fine lines and soften wrinkles, they work in slightly different ways:

Dysport® offers a quick onset and diffuses more easily across larger treatment areas, making it ideal for broader expression lines.
Botox® provides exceptional precision, perfect for targeted wrinkle reduction and refined definition.

During your consultation, we’ll take the time to understand your unique goals, explain the subtle differences between options, and design a treatment plan that’s tailored to your desired outcome. Our mission is to ensure you feel comfortable, informed, and excited about your results from start to finish.

In addition to neuromodulators, our comprehensive medical spa menu includes:

Botox® and Xeomin® injections for wrinkle prevention and correction
Dermal fillers with hyaluronic acid for restoring youthful volume
PCA Skin® chemical peels to smooth texture and brighten skin tone
Microneedling with AnteAGE® growth factors for powerful collagen stimulation

Every treatment is performed with precision and care, ensuring you achieve a refreshed, natural look — never “overdone.”

Serving Littleton, Denver, and surrounding Colorado communities, Columbine Aesthetics is recognized for its client-first approach, rigorous safety standards, and dedication to ongoing education in the latest aesthetic techniques. Whether you want to prevent early signs of aging, rejuvenate your skin, or enjoy a comprehensive facial enhancement plan, our warm and professional environment makes your journey enjoyable and rewarding.

Ready to look and feel your best? Contact Columbine Aesthetics Botox and Medspa in Littleton, CO, today to schedule your personalized consultation and discover why clients trust us for expertise, artistry, and exceptional care.