What to Expect Before, During & After Daxxify

A nurse practitioner performing a Daxxify treatment at Columbine Aesthetics. Learn what to expect before, during, and after your first appointment and call (720) 504-4407 today to schedule your Daxxify consultation.

Summary Highlights:

Personalized consultation and treatment planning by a licensed Nurse Practitioner.
Quick, comfortable procedure with minimal downtime and natural movement.
Advanced Peptide Exchange Technology™ for smoother, longer-lasting results.
Expert guidance for aftercare and combined treatment options.

If you’ve been curious about how Daxxify works and what happens during a treatment session, you’re not alone. At Columbine Aesthetics, many clients ask what they should expect from their first Daxxify appointment—how to prepare, what the treatment feels like, and what kind of aftercare is needed. Because innovative Peptide Exchange Technology™ powers Daxxify, it offers longer-lasting wrinkle reduction and a refined, natural look with fewer maintenance visits. In this blog, I’ll walk you through the entire Daxxify experience—from your consultation to visible results—so you’ll feel informed and confident before your first session.

What Should I Do Before My First Daxxify Appointment?

Before your Daxxify session at Columbine Aesthetics, we’ll begin with a personalized consultation to review your medical history, skin goals, and facial anatomy. This helps us design a treatment plan that’s perfectly suited to your unique features and concerns. Because Daxxify uses a clean, peptide-based formulation with no human or animal proteins, it’s a modern, vegan-friendly option that appeals to many patients looking for advanced wrinkle correction.

To prepare, I recommend avoiding alcohol, blood-thinning medications, and supplements like fish oil or vitamin E for at least 24–48 hours prior. These simple steps help reduce the risk of temporary bruising. Come to your appointment with clean skin—free of makeup or lotions—and be ready to discuss the areas you’d like to treat, such as frown lines, forehead creases, crow’s feet, or chin dimpling. At Columbine Aesthetics, we’ll also discuss your past experiences with injectables (if any) and determine if you’d benefit from combination treatments like dermal fillers or microneedling to enhance your results.

What Happens During a Daxxify Treatment Session?

When you arrive for your Daxxify appointment, our licensed Nurse Practitioner will begin by cleansing and mapping the injection areas. Using a precise and artistic approach, we’ll administer small, controlled doses of botulinum toxin type A, powered by Peptide Exchange Technology™, to relax targeted facial muscles while maintaining your natural expression.

The injection process typically takes less than 20 minutes and is virtually painless—many clients describe it as a quick “pinch” or “tiny pressure.” Because of its innovative peptide stabilizer, Daxxify binds more efficiently to nerve receptors, which helps extend results for up to six to nine months, significantly longer than traditional neurotoxins like Botox or Xeomin. Immediately after treatment, you might notice slight redness or minor swelling, which usually fades within minutes. You can return to your regular activities the same day, making Daxxify an excellent option for those with busy schedules.

What Should I Expect After My Daxxify Treatment?

After your Daxxify injections, results start becoming visible within a few days and continue improving over the next one to two weeks. For most clients, full results appear by week two and can last six months or longer, depending on metabolism, muscle strength, and skincare routine. To ensure the best outcome, I always advise avoiding strenuous exercise, alcohol, and lying flat for several hours post-treatment. Avoid rubbing or massaging the treated areas for at least 24 hours, as this may cause the product to spread unintentionally. Instead, let the neurotoxin settle naturally to deliver smooth, even results.

One of the most significant benefits of choosing Daxxify at Columbine Aesthetics is the effortless aftercare experience. With its longer-lasting formulation, you’ll enjoy consistent wrinkle reduction and won’t need frequent touch-ups throughout the year. It’s ideal for clients who value low-maintenance, high-performance skincare solutions.

Why Choose Columbine Aesthetics for Your First Daxxify Appointment?

At Columbine Aesthetics, every injectable treatment is guided by experience, precision, and artistry. As a nurse practitioner-owned medical aesthetics practice, we take pride in delivering clinically backed care that feels both personal and professional. We don’t just perform Daxxify injections—we craft individualized treatment plans that reflect your natural beauty and lifestyle. Our focus on facial balance, safety, and client education ensures that you’ll leave feeling refreshed, not “frozen.” Plus, our advanced knowledge of Daxxify’s peptide-based technology allows us to achieve long-lasting results with minimal maintenance. When you choose Columbine Aesthetics, you’re choosing an aesthetic partner who truly understands how to enhance your confidence through science, skill, and artistry.

Here’s what sets our approach apart:

Nurse Practitioner Expertise: Every treatment is performed by a licensed medical professional with advanced training in facial anatomy, ensuring precision and safety.
Personalized Treatment Planning: We tailor every Daxxify session to your unique goals, facial structure, and lifestyle for natural-looking, balanced results.
Peptide-Powered Technology: Our deep understanding of Daxxify’s peptide-based innovation allows us to maximize longevity and smoothness for up to six to nine months.
Patient-Centered Experience: From consultation to aftercare, we prioritize your comfort, confidence, and education—so you always feel informed and supported.

Experience Daxxify for Yourself – Call Us

If you’re looking for a wrinkle treatment that lasts longer, feels more natural, and fits easily into your schedule, Daxxify at Columbine Aesthetics is the ideal choice. Our expert team is here to guide you through every step, from your initial consultation to achieving your desired results. We’ll also help you understand the areas that can be treated with Daxxify, including the forehead, frown lines, crow’s feet, and other facial zones where dynamic wrinkles appear most. Call (720) 504-4407 today to schedule your Daxxify consultation or book online through our website. Discover how peptide-powered innovation can help you look refreshed, confident, and beautiful.

FAQs About Daxxify Injections

Common Questions About Botox Injections

What are Daxxify injections and how do they work?

Daxxify injections are an advanced FDA-approved neurotoxin treatment used to smooth moderate to severe frown lines (glabellar lines). Unlike traditional wrinkle relaxers like Botox or Dysport, Daxxify utilizes Peptide Exchange Technology to enhance the botulinum toxin’s binding to nerve receptors, thereby reducing muscle movement that causes wrinkles. This unique formulation allows for longer-lasting results, often extending up to 6 months or more.

How is Daxxify different from Botox, Dysport, or Xeomin?

While Daxxify, Botox, Dysport, and Xeomin are all botulinum toxin-based treatments, Daxxify is the first to use a proprietary stabilizing peptide instead of human or animal-based proteins. This innovation leads to longer-lasting wrinkle reduction, fewer treatments per year, and a cleaner formulation. Patients who want fewer visits and extended results often prefer Daxxify over Botox.

What areas can be treated with Daxxify?

Daxxify injections are currently FDA-approved for treating glabellar lines (frown lines between the eyebrows). Still, providers often use it off-label to treat other facial areas such as forehead lines, crow’s feet, and bunny lines. As with all aesthetic neurotoxins, treatment areas and dosage should be tailored by a skilled medical provider based on your goals and facial anatomy.

How long do the results from Daxxify injections last?

Clinical studies show that Daxxify results can last up to 6 months, with some patients seeing wrinkle reduction for even 9 months or longer. This duration is significantly longer than Botox, which typically lasts 3–4 months. The extended results mean fewer appointments and long-term wrinkle smoothing.

Is Daxxify safe?

Yes, Daxxify is FDA-approved and has undergone extensive clinical testing for safety and efficacy. Like all botulinum toxin treatments, minor side effects may include temporary redness, swelling, or tenderness at the injection site. It’s important to have Daxxify administered by a licensed medical professional to minimize risk and ensure optimal results.

Who is a good candidate for Daxxify injections?

Ideal candidates for Daxxify are adults who want to reduce facial wrinkles, especially between the brows, and are seeking longer-lasting alternatives to Botox. It’s also an excellent option for those new to anti-aging injections, as it offers a more extended treatment window with fewer touch-ups. Patients should be in good overall health and have realistic expectations.

How much do Daxxify injections cost?

At Columbine Aesthetics, Daxxify is priced at $11 per unit, with the total cost depending on the treatment area and units used. While Daxxify may have a slightly higher upfront price compared to other neurotoxins, its longer duration means fewer sessions over the course of a year, making it a valuable investment in youthful skin longevity.

What is the downtime or recovery like with Daxxify?

Daxxify is a minimally invasive treatment with virtually no downtime. Most clients return to normal activities immediately after their session. Some may experience mild bruising or swelling at the injection site, which typically resolves within a few hours to a day. For best results, avoid lying down or engaging in strenuous activity for approximately 4 hours after the injection.

Can Daxxify be combined with other cosmetic treatments?

Yes, Daxxify can safely be combined with other aesthetic services such as dermal fillers, microneedling, chemical peels, or medical-grade skincare to create a comprehensive anti-aging treatment plan. At Columbine Aesthetics, your treatment is customized to align with your goals, ensuring synergistic results and skin rejuvenation.

Why should I get Daxxify injections at Columbine Aesthetics?

At Columbine Aesthetics, your Daxxify treatment is performed by a licensed Nurse Practitioner with deep clinical knowledge of facial anatomy and injectables. We prioritize natural-looking results, safety, and personalized care. You’ll also benefit from expert guidance on how Daxxify fits into your broader anti-aging and skincare routine, all in a supportive, patient-first environment.

Why Trust Columbine Aesthetics

At Columbine Aesthetics, we believe your aesthetic journey should be as unique as you are. Led by Allison Page, NP-C, our highly skilled Nurse Practitioner with over 20 years of healthcare experience, we combine medical expertise with an artistic eye to deliver natural, beautiful results that enhance — not alter — your appearance.

We specialize in helping clients make informed, confident decisions about treatments such as Dysport® and Botox®. While both smooth fine lines and soften wrinkles, they work in slightly different ways:

Dysport® offers a quick onset and diffuses more easily across larger treatment areas, making it ideal for broader expression lines.
Botox® provides exceptional precision, perfect for targeted wrinkle reduction and refined definition.

During your consultation, we’ll take the time to understand your unique goals, explain the subtle differences between options, and design a treatment plan that’s tailored to your desired outcome. Our mission is to ensure you feel comfortable, informed, and excited about your results from start to finish.

In addition to neuromodulators, our comprehensive medical spa menu includes:

Botox® and Xeomin® injections for wrinkle prevention and correction
Dermal fillers with hyaluronic acid for restoring youthful volume
PCA Skin® chemical peels to smooth texture and brighten skin tone
Microneedling with AnteAGE® growth factors for powerful collagen stimulation

Every treatment is performed with precision and care, ensuring you achieve a refreshed, natural look — never “overdone.”

Serving Littleton, Denver, and surrounding Colorado communities, Columbine Aesthetics is recognized for its client-first approach, rigorous safety standards, and dedication to ongoing education in the latest aesthetic techniques. Whether you want to prevent early signs of aging, rejuvenate your skin, or enjoy a comprehensive facial enhancement plan, our warm and professional environment makes your journey enjoyable and rewarding.

Ready to look and feel your best? Contact Columbine Aesthetics Botox and Medspa in Littleton, CO, today to schedule your personalized consultation and discover why clients trust us for expertise, artistry, and exceptional care.