How Daxxify’s Peptide Technology Differs from Botox and Xeomin

Explore how Columbine Aesthetics offers Daxxify with peptide technology that lasts longer than Botox or Xeomin. Call (720) 504-4407 today to book your wrinkle treatment.

Summary Highlights:

Explore how Daxxify’s peptide-powered formula sets it apart from traditional neurotoxins.
Learn why Peptide Exchange Technology™ provides longer-lasting wrinkle reduction.
Understand the key differences between Daxxify, Botox, and Xeomin.
See how Columbine Aesthetics delivers natural results with advanced injection expertise.

When I first heard about Daxxify injections, I was intrigued by how they differ from traditional wrinkle treatments, such as Botox and Xeomin. At Columbine Aesthetics, we’re passionate about bringing the latest advancements in anti-aging to our patients, and Daxxify represents one of the most exciting innovations yet. Using Peptide Exchange Technology, this treatment provides longer-lasting, natural results that distinguish it from other botulinum toxin type A injectables.

What makes Daxxify’s peptide technology unique compared to Botox and Xeomin?

Unlike Botox and Xeomin, which rely on traditional stabilizers such as human serum albumin, Daxxify is powered by a clean, peptide-based formula. Its Peptide Exchange Technology™ helps stabilize the active ingredient without animal or human-derived proteins, making it a vegan-friendly neurotoxin option. This innovation enhances how Daxxify binds to nerve receptors, leading to smoother lines and increased longevity.

Patients often ask me why this matters. The answer is simple: a cleaner formulation means less risk for those with sensitivities, and the peptide component is what makes Daxxify injections a true breakthrough in wrinkle reduction.

How long do Daxxify results last compared to Botox and Xeomin?

One of the most important differences I explain to my patients is the duration of results. While Botox and Xeomin typically last around 3–4 months, Daxxify often provides visible wrinkle smoothing for 6 months or longer. In clinical studies, some patients even experienced Daxxify results lasting up to 9 months.
For busy professionals, parents, and anyone who values low-maintenance beauty, this means fewer appointments each year and more consistent results. At Columbine Aesthetics, we’ve seen firsthand how our patients love not having to schedule touch-ups as frequently as they did with Botox or Xeomin.

Is Daxxify just as safe as Botox and Xeomin?

Yes, absolutely. Daxxify is FDA-approved for glabellar lines (the frown lines between the eyebrows) and has undergone extensive clinical studies. Like all neurotoxin injections, minor side effects such as redness, swelling, or mild bruising may occur, but they usually subside within a couple of days. The difference at Columbine Aesthetics is that a licensed Nurse Practitioner performs all injections with specialized training in facial anatomy. This ensures your treatment looks natural and never “frozen.” Safety, precision, and artistry are at the heart of every appointment we provide.

Areas treated with Daxxify?

Although Daxxify is FDA-approved specifically for frown lines, many skilled practitioners (like those at Columbine Aesthetics) use it off-label to smooth:

Forehead creases
Crow’s feet
Bunny lines on the nose
Chin dimpling
Neck bands

By tailoring each treatment plan to your unique needs, we can use Daxxify as part of a complete anti-aging strategy. This flexibility is another reason it has become such a popular choice for our patients.

Why should I choose Columbine Aesthetics for Daxxify injections?

At Columbine Aesthetics, we don’t just offer wrinkle injections—we provide personalized care backed by medical expertise. Every consultation begins with a one-on-one assessment to understand your goals. We then design a treatment plan that not only includes Daxxify, but may also combine complementary services such as fillers, skin peels, or medical-grade skincare for enhanced results. Our mission is simple: to help you feel confident, refreshed, and naturally beautiful. With Daxxify’s advanced peptide-powered formula, we can deliver results that last longer and look more natural than ever.

Experience the Benefits of Daxxify’s Peptide Technology

If you’ve been curious about trying a modern alternative to Botox and Xeomin, Daxxify could be the solution you’ve been waiting for. Its unique Peptide Exchange Technology™, longer-lasting results, and clean, vegan-friendly formula make it a standout option in today’s world of wrinkle treatments. At Columbine Aesthetics, we’re excited to offer this cutting-edge injectable to our patients. Let us show you how Daxxify can fit into your lifestyle and help you achieve smoother, more youthful-looking skin with fewer appointments.

Ready to experience the future of wrinkle reduction? Call us today at (720) 504-4407 to schedule your personalized consultation and see why Daxxify is quickly becoming the go-to choice for lasting beauty.

FAQs About Daxxify Injections

Common Questions About Botox Injections

What are Daxxify injections and how do they work?

Daxxify injections are an advanced FDA-approved neurotoxin treatment used to smooth moderate to severe frown lines (glabellar lines). Unlike traditional wrinkle relaxers like Botox or Dysport, Daxxify utilizes Peptide Exchange Technology to enhance the botulinum toxin’s binding to nerve receptors, thereby reducing muscle movement that causes wrinkles. This unique formulation allows for longer-lasting results, often extending up to 6 months or more.

How is Daxxify different from Botox, Dysport, or Xeomin?

While Daxxify, Botox, Dysport, and Xeomin are all botulinum toxin-based treatments, Daxxify is the first to use a proprietary stabilizing peptide instead of human or animal-based proteins. This innovation leads to longer-lasting wrinkle reduction, fewer treatments per year, and a cleaner formulation. Patients who want fewer visits and extended results often prefer Daxxify over Botox.

What areas can be treated with Daxxify?

Daxxify injections are currently FDA-approved for treating glabellar lines (frown lines between the eyebrows). Still, providers often use it off-label to treat other facial areas such as forehead lines, crow’s feet, and bunny lines. As with all aesthetic neurotoxins, treatment areas and dosage should be tailored by a skilled medical provider based on your goals and facial anatomy.

How long do the results from Daxxify injections last?

Clinical studies show that Daxxify results can last up to 6 months, with some patients seeing wrinkle reduction for even 9 months or longer. This duration is significantly longer than Botox, which typically lasts 3–4 months. The extended results mean fewer appointments and long-term wrinkle smoothing.

Is Daxxify safe?

Yes, Daxxify is FDA-approved and has undergone extensive clinical testing for safety and efficacy. Like all botulinum toxin treatments, minor side effects may include temporary redness, swelling, or tenderness at the injection site. It’s important to have Daxxify administered by a licensed medical professional to minimize risk and ensure optimal results.

Who is a good candidate for Daxxify injections?

Ideal candidates for Daxxify are adults who want to reduce facial wrinkles, especially between the brows, and are seeking longer-lasting alternatives to Botox. It’s also an excellent option for those new to anti-aging injections, as it offers a more extended treatment window with fewer touch-ups. Patients should be in good overall health and have realistic expectations.

How much do Daxxify injections cost?

At Columbine Aesthetics, Daxxify is priced at $11 per unit, with the total cost depending on the treatment area and units used. While Daxxify may have a slightly higher upfront price compared to other neurotoxins, its longer duration means fewer sessions over the course of a year, making it a valuable investment in youthful skin longevity.

What is the downtime or recovery like with Daxxify?

Daxxify is a minimally invasive treatment with virtually no downtime. Most clients return to normal activities immediately after their session. Some may experience mild bruising or swelling at the injection site, which typically resolves within a few hours to a day. For best results, avoid lying down or engaging in strenuous activity for approximately 4 hours after the injection.

Can Daxxify be combined with other cosmetic treatments?

Yes, Daxxify can safely be combined with other aesthetic services such as dermal fillers, microneedling, chemical peels, or medical-grade skincare to create a comprehensive anti-aging treatment plan. At Columbine Aesthetics, your treatment is customized to align with your goals, ensuring synergistic results and skin rejuvenation.

Why should I get Daxxify injections at Columbine Aesthetics?

At Columbine Aesthetics, your Daxxify treatment is performed by a licensed Nurse Practitioner with deep clinical knowledge of facial anatomy and injectables. We prioritize natural-looking results, safety, and personalized care. You’ll also benefit from expert guidance on how Daxxify fits into your broader anti-aging and skincare routine, all in a supportive, patient-first environment.

Why Trust Columbine Aesthetics

At Columbine Aesthetics, we believe your aesthetic journey should be as unique as you are. Led by Allison Page, NP-C, our highly skilled Nurse Practitioner with over 20 years of healthcare experience, we combine medical expertise with an artistic eye to deliver natural, beautiful results that enhance — not alter — your appearance.

We specialize in helping clients make informed, confident decisions about treatments such as Dysport® and Botox®. While both smooth fine lines and soften wrinkles, they work in slightly different ways:

Dysport® offers a quick onset and diffuses more easily across larger treatment areas, making it ideal for broader expression lines.
Botox® provides exceptional precision, perfect for targeted wrinkle reduction and refined definition.

During your consultation, we’ll take the time to understand your unique goals, explain the subtle differences between options, and design a treatment plan that’s tailored to your desired outcome. Our mission is to ensure you feel comfortable, informed, and excited about your results from start to finish.

In addition to neuromodulators, our comprehensive medical spa menu includes:

Botox® and Xeomin® injections for wrinkle prevention and correction
Dermal fillers with hyaluronic acid for restoring youthful volume
PCA Skin® chemical peels to smooth texture and brighten skin tone
Microneedling with AnteAGE® growth factors for powerful collagen stimulation

Every treatment is performed with precision and care, ensuring you achieve a refreshed, natural look — never “overdone.”

Serving Littleton, Denver, and surrounding Colorado communities, Columbine Aesthetics is recognized for its client-first approach, rigorous safety standards, and dedication to ongoing education in the latest aesthetic techniques. Whether you want to prevent early signs of aging, rejuvenate your skin, or enjoy a comprehensive facial enhancement plan, our warm and professional environment makes your journey enjoyable and rewarding.

Ready to look and feel your best? Contact Columbine Aesthetics Botox and Medspa in Littleton, CO, today to schedule your personalized consultation and discover why clients trust us for expertise, artistry, and exceptional care.