Image showing Daxxify treatment areas on the face. Learn how Columbine Aesthetics uses peptide-powered Daxxify injections to smooth wrinkles and fine lines for months. Call (720) 504-4407 to schedule your consultation today.

Summary Highlights:

  • Daxxify treats multiple areas: forehead, frown lines, crow’s feet, chin, and neck.
  • Results can last up to six to nine months—double the duration of other neurotoxins.
  • Peptide Exchange Technology™ delivers smoother, natural, and longer-lasting results.
  • Columbine Aesthetics ensures expert, medically guided care for every treatment area.

If you’ve been curious about where Daxxify can be used and how it compares to Botox or Xeomin, you’re not alone. At Columbine Aesthetics, we’ve seen a growing number of clients asking which treatment areas deliver the most noticeable and longest-lasting results. Since cutting-edge Peptide Exchange Technology™ powers Daxxify, it offers a fresh approach to wrinkle reduction—one that’s both longer-lasting and naturally expressive. What makes it even more exciting is how its advanced formulation allows precise, customizable treatment across multiple facial zones, helping us refine expression lines without compromising your natural movement.

What Makes Daxxify Different from Other Wrinkle Relaxers?

Daxxify is the first and only peptide-powered neurotoxin—a major innovation in the world of injectables. Like Botox and Xeomin, it contains botulinum toxin type A, but instead of being stabilized with human or animal proteins, it uses a clean, vegan peptide formulation. This advancement enables Daxxify to bind more effectively to nerve receptors, providing faster onset and smoother results while also extending longevity. Many of our clients enjoy visible wrinkle reduction for six months or longer, meaning fewer touch-ups and consistent results year-round.

What Are the Most Common Areas Treated with Daxxify?

Currently, Daxxify is FDA-approved for glabellar lines (the frown lines between your eyebrows). However, experienced injectors—like our licensed Nurse Practitioner at Columbine Aesthetics—can skillfully use Daxxify in other areas to achieve full-face rejuvenation. Here are the most popular treatment areas:

  • Forehead Lines (Frontalis Muscle): These horizontal creases form when we raise our eyebrows. Daxxify smooths these lines beautifully, giving a relaxed yet natural expression. Due to its peptide technology, the results remain consistent even as the product wears off gradually.
  • Frown Lines (Glabellar Area): The “11s” between your brows can make you look stressed or tired. Daxxify effectively relaxes these muscles, softening your expression while maintaining a natural look.
  • Crow’s Feet (Outer Corners of the Eyes): Daxxify smooths these fine lines without making your eyes appear frozen. Its longevity makes it a favorite among clients seeking to maintain bright, youthful eyes with fewer visits.
  • Bunny Lines (Upper Nose): These small wrinkles appear when scrunching your nose. A few precisely placed units of Daxxify help smooth them while preserving natural facial movement.
  • Chin Dimpling (Mentalis Muscle): The “orange peel” texture that sometimes appears on the chin can be softened effectively with Daxxify injections, creating a smoother lower-face profile.
  • Neck Bands (Platysmal Bands): Though an off-label use, Daxxify can help relax vertical neck bands and improve the appearance of sagging skin for a smoother neckline.

At Columbine Aesthetics, every Daxxify treatment plan is tailored to your facial anatomy and goals, ensuring results that look refreshed—not overdone.

Which Areas Deliver the Best Results with Daxxify?

While Daxxify performs impressively across multiple facial zones, some areas tend to show especially outstanding and long-lasting outcomes:
Glabellar lines: Clinical studies show Daxxify results here can last twice as long as traditional neurotoxins.

  • Forehead wrinkles: Because of its peptide-based stability, smoothing remains even as the product gradually fades.
  • Crow’s feet: Clients notice a natural brightness around the eyes without stiffness or heaviness.

The key advantage lies in Daxxify’s ability to maintain consistent relaxation over time. You’ll notice smoother, more even skin tone and texture well beyond the typical 3–4-month window seen with other neurotoxins.

How Long Do Daxxify Results Last by Area?

Most clients begin noticing visible improvements within just a few days, with full results appearing around the two-week mark. Depending on factors such as metabolism, muscle strength, and lifestyle, Daxxify results can last an impressive six to nine months—particularly in areas like the glabella (between the brows) and forehead, where muscle movement is most consistent. Because of this extended longevity, Daxxify is an excellent option for busy professionals who prefer fewer maintenance appointments, clients who travel frequently, and anyone seeking year-round wrinkle reduction with minimal touch-ups or downtime.

Is Daxxify Safe for All Treatment Areas?

Yes. Daxxify is FDA-approved for frown lines and widely regarded as safe for off-label facial areas when performed by a skilled, medically trained injector. At Columbine Aesthetics, all injections are administered by our Nurse Practitioner, who has advanced knowledge of facial anatomy and aesthetic balance. We also follow strict medical protocols to ensure comfort, symmetry, and safety in every treatment session. While most clients experience little to no downtime, we always discuss Daxxify’s common side effects—such as mild redness, swelling, or temporary tenderness—so you know exactly what to expect before and after your appointment.

Why Choose Columbine Aesthetics for Daxxify?

Choosing the right injector is key to achieving balanced, natural-looking results. At Columbine Aesthetics, we’re passionate about pairing innovative treatments with personalized care. Our approach focuses on:

  • Individualized assessment of facial structure and muscle movement
  • Precision dosing for each treatment area
  • Maintaining expression and harmony between facial features
  • Ensuring long-term satisfaction through follow-up and skincare guidance

Whether you want to refresh a few fine lines or smooth multiple areas for a youthful glow, we’ll create a treatment plan tailored specifically to you.

Discover What Daxxify Can Do for You – Call Us Today

If you’re ready to experience longer-lasting wrinkle smoothing with fewer appointments, Daxxify could be your perfect match. At Columbine Aesthetics, we’ll walk you through every step—from consultation to post-treatment care—so you can feel confident and informed. With Daxxify, you can enjoy smoother lines, renewed confidence, and natural results that truly last. Call (720) 504-4407 today to schedule your Daxxify consultation or book online through our website.

FAQs About Daxxify Injections

Common Questions About Botox Injections

Daxxify injections are an advanced FDA-approved neurotoxin treatment used to smooth moderate to severe frown lines (glabellar lines). Unlike traditional wrinkle relaxers like Botox or Dysport, Daxxify utilizes Peptide Exchange Technology to enhance the botulinum toxin’s binding to nerve receptors, thereby reducing muscle movement that causes wrinkles. This unique formulation allows for longer-lasting results, often extending up to 6 months or more.
While Daxxify, Botox, Dysport, and Xeomin are all botulinum toxin-based treatments, Daxxify is the first to use a proprietary stabilizing peptide instead of human or animal-based proteins. This innovation leads to longer-lasting wrinkle reduction, fewer treatments per year, and a cleaner formulation. Patients who want fewer visits and extended results often prefer Daxxify over Botox.
Daxxify injections are currently FDA-approved for treating glabellar lines (frown lines between the eyebrows). Still, providers often use it off-label to treat other facial areas such as forehead lines, crow’s feet, and bunny lines. As with all aesthetic neurotoxins, treatment areas and dosage should be tailored by a skilled medical provider based on your goals and facial anatomy.
Clinical studies show that Daxxify results can last up to 6 months, with some patients seeing wrinkle reduction for even 9 months or longer. This duration is significantly longer than Botox, which typically lasts 3–4 months. The extended results mean fewer appointments and long-term wrinkle smoothing.
Yes, Daxxify is FDA-approved and has undergone extensive clinical testing for safety and efficacy. Like all botulinum toxin treatments, minor side effects may include temporary redness, swelling, or tenderness at the injection site. It’s important to have Daxxify administered by a licensed medical professional to minimize risk and ensure optimal results.
Ideal candidates for Daxxify are adults who want to reduce facial wrinkles, especially between the brows, and are seeking longer-lasting alternatives to Botox. It’s also an excellent option for those new to anti-aging injections, as it offers a more extended treatment window with fewer touch-ups. Patients should be in good overall health and have realistic expectations.
At Columbine Aesthetics, Daxxify is priced at $11 per unit, with the total cost depending on the treatment area and units used. While Daxxify may have a slightly higher upfront price compared to other neurotoxins, its longer duration means fewer sessions over the course of a year, making it a valuable investment in youthful skin longevity.
Daxxify is a minimally invasive treatment with virtually no downtime. Most clients return to normal activities immediately after their session. Some may experience mild bruising or swelling at the injection site, which typically resolves within a few hours to a day. For best results, avoid lying down or engaging in strenuous activity for approximately 4 hours after the injection.
Yes, Daxxify can safely be combined with other aesthetic services such as dermal fillers, microneedling, chemical peels, or medical-grade skincare to create a comprehensive anti-aging treatment plan. At Columbine Aesthetics, your treatment is customized to align with your goals, ensuring synergistic results and skin rejuvenation.
At Columbine Aesthetics, your Daxxify treatment is performed by a licensed Nurse Practitioner with deep clinical knowledge of facial anatomy and injectables. We prioritize natural-looking results, safety, and personalized care. You’ll also benefit from expert guidance on how Daxxify fits into your broader anti-aging and skincare routine, all in a supportive, patient-first environment.

Why Trust Columbine Aesthetics

At Columbine Aesthetics, we believe your aesthetic journey should be as unique as you are. Led by Allison Page, NP-C, our highly skilled Nurse Practitioner with over 20 years of healthcare experience, we combine medical expertise with an artistic eye to deliver natural, beautiful results that enhance — not alter — your appearance.

We specialize in helping clients make informed, confident decisions about treatments such as Dysport® and Botox®. While both smooth fine lines and soften wrinkles, they work in slightly different ways:

  • Dysport® offers a quick onset and diffuses more easily across larger treatment areas, making it ideal for broader expression lines.
  • Botox® provides exceptional precision, perfect for targeted wrinkle reduction and refined definition.

During your consultation, we’ll take the time to understand your unique goals, explain the subtle differences between options, and design a treatment plan that’s tailored to your desired outcome. Our mission is to ensure you feel comfortable, informed, and excited about your results from start to finish.

In addition to neuromodulators, our comprehensive medical spa menu includes:

  • Botox® and Xeomin® injections for wrinkle prevention and correction
  • Dermal fillers with hyaluronic acid for restoring youthful volume
  • PCA Skin® chemical peels to smooth texture and brighten skin tone
  • Microneedling with AnteAGE® growth factors for powerful collagen stimulation

Every treatment is performed with precision and care, ensuring you achieve a refreshed, natural look — never “overdone.”

Serving Littleton, Denver, and surrounding Colorado communities, Columbine Aesthetics is recognized for its client-first approach, rigorous safety standards, and dedication to ongoing education in the latest aesthetic techniques. Whether you want to prevent early signs of aging, rejuvenate your skin, or enjoy a comprehensive facial enhancement plan, our warm and professional environment makes your journey enjoyable and rewarding.

Ready to look and feel your best? Contact Columbine Aesthetics Botox and Medspa in Littleton, CO, today to schedule your personalized consultation and discover why clients trust us for expertise, artistry, and exceptional care.